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With respect to the requested changes to the present restriction’s diagnostic standards for narcolepsy, the PBAC acknowledged the pre-Sub-Committee response argument that "the MSLT is neither perfectly delicate nor particular for the analysis of narcolepsy", and as such patients may be misdiagnosed and denied treatment, and that because the MSLT was solely obtainable in main centres it was an inappropriate requirement for the restriction. The PBAC subsequently rejected the appliance because of insufficient proof to support the declare that placebo rather than dexamphetamine is the appropriate comparator for modafinil in the first line setting and due to inadequate evidence to substantiate the declare that eligible patients are being denied remedy under the current restriction. In March 2008 a joint working social gathering between the ASA and ANZAN was established to assessment the present availability of modafinil for the treatment of narcolepsy in Australia. The Australian Sleep Association (ASA) and the Australian New Zealand Affiliation of Neurologists (ANZAN) joint working occasion is disappointed by the PBAC rejection. The PBAC welcomed the submission from the Australian Sleep Affiliation (ASA) and the Australian New Zealand Association of Neurologists (ANZAN) joint working celebration and indicated its empathy with the position put forward by this group.